Yep, we've stopped at the Super Target on our last two trips "home". It has been great for us. We like to pick up cheap toiletries there too - I'd buy 'em at Target here, so why not just buy 'em there? We like to pick a special shampoo/conditioner that has a unique scent (like a crazy reaspberry or somthing we normally wouldnt get at home) so that when we get home all we have to do is go to Target and sniff the shampoo and re-live a bit of vacation. Weird, I know...but hey, it works for us!
Oh, its also great for those things you remember that you forgot to pack while you are on the plane (socks, cold medicine, etc.)
Enjoy!