I've used Afrin....actually used it back when it was a prescription drug. And I got addicted to it. Used it every day...several times a day. I couldn't breath without it. Finally went to an allergist about it...his question to me was this..
'Have you ever used cocaine??' Seems my membranes looked exactly like those of a coke addict's nose!! A bit scary!! I managed to get off the Afrin and use it only very occasionally in order to sleep if I'm really congested.
But...I would imagine that while Afrin isn't an antibiotic, it would prevent the build up of mucus, which would help prevent an infection in the sinuses. But, it might be worthwhile to think about an allergy decongestant. I like Tylenol Sinus..it works really well. I take it before flying now...just in case. It seems to help prevent any congestion from building up.
That's a good point Diane - I actually use decongestants with pseudophedrine in them to relieve my allergy symptoms and sinus swelling. I used Drixoral for over 20 years, but that was discontinued a few years ago, so now I use Zyrtec-D. Pseudophedrine doesn't have the "rebounding" effect that a vasoconstrictor like Afrin has, so it's not addictive. With my many, many allergies, and my sinuses being so sensitive to weather changes (I get pressure headaches EVERY time a weather front moves through), I wind up taking a Zyrtec-D several times a week. During the spring and fall allergy seasons, there are periods of a couple of weeks where I take it every day.
I seriously doubt that vasoconstrictors like Afrin have ANY effect on infection. Mucus buildup only happens if you're already infected, anyway, so even if Afrin prevents mucus buildup - in my experience, it actually does the opposite - you'd already be infected, anyway. Using it for temporary relief from nasal swelling is fine, but don't count on something with no antibiotic properties to prevent or cure an infection, because it won't. It will only provide temporary relief from one symptom of those infections.
Yes, I use Afrin, though I use it sparingly and at 1/3 the dose recommended on the bottle, when I need instant relief and can't wait for the pseudophedrine to kick in. And I have wound up with damage to my nasal membranes whenever I've over-used it.
Before leaving home to get on a plane, I take a Zyrtec-D to mitigate any allergy symptoms I might have from travelling and prevent sinus swelling from the pressure changes, and I may take a low dose of Afrin, if my nasal passages are swollen. Fortunately, I've never had any ear trouble while flying, but if I ever do, I'll try EarPlanes, and I'll see my doctor for some ear drops.