My son has been on prilosec for 2 years by prescription. It has worked well for him and he has really bad reflux. By prescription we were paying $30 per month (insurance) but now that it is OTC it will be about $42 per month since he takes 40 mg (2 capsules.) But, being OTC, if he runs out while at school, he can just go to CVS and buy it. Our pharmacist is not sure if we can still get it by prescription and save $12. Your DH may want to talk with his doctor.