Singing mom- I think you will find it challenging to completely unpack and re pack on an
ABD. As you know the pace is very fast, rarely more than 2 nights in a place. So everytime you move to a new hotel you have to spend so much time re packing.
BAGGING IT: I know its hard to "live" out of a suitcase, but you could try as Tuf Buf suggest packing in smaller, item specific bags so that you only have to pack the bags or packing cubes back up rather than packing individual items. For instance I pack my underware and socks in one bag, tees in another, laundry in another etc, that way I can move the bags out of the suitcase (unpack) or if I chose to live out of the bag, I don't have to upend everything to get to the stuff at the bottom. I just remove a bag or two and can reach everything. Like you I pack toiletires in puches by function, that way first aid and meds don't need to live in a small bath, and I can leave the "bag" with shower stuff in the shower. I keep all the gels in one so I can show it off at the airport.
MIX AND MATCH: I have lots of travel clothing that is all in the same color family. This way I can do as you like to Singing mom and "decide" on my outfit on the fly. I have 2-3 pants, 4-5 shirts and a couple of sweaters/jackets. These all match the same shoe. That way I can put it together based on the day, but I know it will mostly go together. I have a collection of easy care, lightweight stuff now, and I bag it!
Now I have a completely different recommendation for packing for young children-
If you are doing an ABD with little kids it is far, far easier to pack by outfit. They usually get so grubby you cant repeat much anyway (maybe wear shorts 2 days,) Look at the itinerary, and put together an outfit that works for that day in a large plastic bag, label the day and whats in it it (yellow shirt, cargo shorts, put the underware and socks in there too!) so if you do laundry you can put it back in the bag afterwards. This is great because you will have many early mornings and all one needs to do is hand your child their bag and they dress (or for the littlest kids, hand the bag to a big or co parent and you don't have to micromanage everyone getting ready) The dirty stuff goes right back in the bag at the end of the day, so the kids don't have piles of dirty laundry everywhere to pack on moving day. It simplifies things soooo much!
BTW Richflower- the 2 1/2 gallon zip lock bags really do the same job for a lot less $$