Then you will be going through Greensboro and Asheboro. There are alot of exits in Greensboro. A good one (although busy) is the Wendover West exit. It has many hotels and restaurants.
Asheboro is a smaller town but is not as busy. The NC zoo is located there. You will pass Greensboro first, this will be on 40 east. Soon after you will take 220 south toward Asheboro. If you decide on Asheboro you will take the exit that says Raleigh US Hwy 64 east. Go right off of the ramp, you will see a Burger King, McDonalds and some other fast food places. About a mile further down the road (Dixie Drive) there is a very nice Hampton Inn and a Holiday Inn Express. There are a couple more but I'm not sure about the quality of them. There is a Wal-Mart supercenter on the right past the 2 hotels I mentioned. There is also a small mall about a mile further on the left.
There are several good places to eat. The American Roadhouse has good food and it is a local place. There is also Chilis, Pizza Hut, KFC, Cookout, Arbys, Taco Bell, CiCi's Pizza, Chinese buffet (the one in the
walmart strip is good), Papa Johns, Dominos, and a Golden Corral.
I would choose the Asheboro exit over the Greensboro because of the traffic and it is easier to get around.
There is also a WalMart, McDonalds, Taco Bell, Hardees, Wendy's, Subway and Bojangles on the Randleman exit which is a few miles before Asheboro. But there are not any hotels there.
Sadie
Myrtle Beach is about 3 hours from Asheboro.