The big differences are that the lock off room is a stand alone studio, thus it will have a mini kitchen with a microwave, coffee pot, and mini fridge. You will also have a locking door between the 1BR and the studio with an external door. HTH
We loved the huge walk in closet Instead of the exterior entrance in the lock-off part of the 2nd bedroom, also the nice outside vanity area in place of the kitchenette....worked well for us.
The lockoff second bedroom has the tiny closet. The dedicated second bedroom has a room sized closet as well as the tiny closet opposite where the kitchenette would be.