Cool, I live right near there!
Busch Gardens is great. But don't ride the Congo River Rapids. The water is disgusting!
Make sure to ride Sheikra and Kumba. They're the best. Don't bother with Pirates 4-D, it's SO boring.
Are you going to Adventure Island? My cousin works as a shallow water guard there. My fave rides are Wahoo Run (Up to five person raft ride) and Key West Rapids (Open slide that you ride on tubes). Runaway Rapids (The normal plain slides, I call them the Butt Slides lol) are cool too.
You can also visit the aquarium, lowry park zoo, MOSI, and Ybor. If you're looking for a place to stay, I'd suggest the Mariott by the aquarium in downtown. It's right by the trolley too.