Just at WL and VWL... the in-room safes are not large enough for a laptop, not even a small one. The desk does have a safe with individual boxes you can use if you don't mind stoping off there on the way in/out. It can be slightly more time consuming if there's a line, but if your computer and/or it's contents are that valuable you may consider it. I used this after checking out as I didn't trust the valet stand with my luggage out on the curb while we went off to the park for one last look.
AKV, (and my bet is AKL also) being the newest does have large in-room safes that will fit even the larger screen laptops, but I see that's not among your choices for '08 in your siggy.