Be careful.....I've found Hotwire often to be more expensive than searching websites for the vendor's own best price. Priceline, it seems, often will offer some real bargains. If you can figure out which hotel Hotwire is offering, look at that hotel's website. Figure in the service fees to see if it is really a great deal.
I know some people have gotten great deals with HW, but you can almost always beat the price by bidding with PL, and sometimes by booking directly. Last thing I checked on HW was cars....they were a lot higher than the car vendors themselves, and that wasn't even taking into account the service fees.