I have extreme motion sickness...can't even ride in the back seat of a vehicle. I take Transderm Scop...scopolamine 1.5 mg. It is a patch that you put behind your ear and you can wear it for 72 hours. I LOVE IT! I wear it everytime we go to Disney World. The only down side is that it impedes your vision (which is what makes it work). Your vision doesn't quite focus right. It is a little difficult to focus on menus and small prints...but sooo totally worth it. You are drowsy for the first 4 hours or so...but I take it on the way there, so I am usually refreshed from my nap by the time we arrive.