Three quickly come to mind. There is a LaQuinta and a Wingate (Wyndham) that are side by side and an Embassy Suites that's just across Fowler Avenue from them - all near the University of South Florida campus. They are about two miles from Busch Gardens.
I have stayed at the Embassy Suites near USF and it was beautiful. I would say to stay there. The LaQuinta and a Wingate may be cheaper, I don't know. I have never stayed at either of them.
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