Booking hotel rooms using Priceline (or something similar)

[scrapbookmommy]

I need to book an inexpensive room for our first night in Orlando and for two nights in Daytona. As soon as we make it through next week to know our schools won't be cancelled from any more flooding I plan to do this. Are there any tips or tricks I need to know before using one of these sites? Is Priceline who I should use or does someone else have other suggestions. As you can tell this will be my first time booking a room through this type of site. TIA