We stayed in the Ayers Anaheim which is on Katella about 2 miles down the road from DLR. This was a few years ago when it was new and we loved it. I would highly recommend it. We always take mid day breaks and it was a 5 min drive (we always rent a car). It is definitely not walking distance. This hotel is also now rated #1 in Anaheim on Tripadvisor now and I'm not surprised.
If it is the Ayers Orange you are looking at it is an older property than the Anaheim one, and farther away. I haven't stayed there, but I think all Ayers hotels have high quality. People often get the 2 confused.
Breakfast was great, the rooms are lovely (very Euro-boutique hotel feel), with microwave, fridge, coffee maker, etc. There was also a laundry right down the hall. The pool is nothing special but kids will think it is fine.