We just sailed last week on the Fantasy Western, and I was very concerned about motion sickness since it was my first cruise and I am prone to nausea on things that move. We were midship deck 7, and although I felt 'weird' the first night due to the new sensation and because my husband said we were going through the Gulf Stream that first night so it was the most we noticed it, I actually never felt sick at any point during the cruise. With a ship that large and the stabilizers, you honestly don't even know you're on a ship most of the time, and we were lucky to have very calm seas all week long. The slight rocking motion I may have felt during the night actually helped me have the best sleep I've had in ages. I did take non-drowsy Dramamine the first day just in case, and on both our sea days, so I don't know if they helped or were more of a placebo for me. Everyone is different though, so take the medications you think might help. September was a cheaper time for us to book.