Lisa:
Vacation homes can only be rented in restricted areas of the Orlando area, none of which exist very close to Universal... believe me I checked!
I think that the vacation home experience is worth it, though, so I deal with the commute. I feel like I live there when I'm at one!
Your best bet is to rent one closest to the Disney area and close to I-4. Can't do much better than than, though.
Email me if you want more information.
Robin