It's been a while since I drove that route but I'd say just under two hours from Center City... getting out of Philly is the most time-consuming part... You head north toward Allentown (via the turnpike) and then east. Does that sound about right, Philly people?How far is the Crayola Factory from central Philadelphia? We will be there this summer visiting my sister and that sounds like a fun place to go. Thanks!!