Since the safe is not big enough for my laptop, what I do when I stay at a Value resort is this:
I have a standard laptop locking cable, which I got from CompUSA (you can get them just about anywhere that sells laptops and accessories). I weave the cable in and out among the individual wires of the shelf in the vanity area and leave the laptop locked to it.
This doesn't make it impossible to steal, but it makes it impossible to steal without big bolt cutters. The locking cables are stranded steel cable, and I always weave the cable among 7 or 8 tines of the shelf so that anybody who wants to take the laptop woud have to cut through a bunch of them.