No.
And you can see in, my signature how many times we have stayed at Disney hotels...all levels. We always have at least 2 laptops, and 1 or 2 kindles in our room. We do not lock them up, just keep them out of sight.
We also drive back & forth to Florida several times a year, staying in hotels approximately 8-10 additional nights...and do some traveling around Florida too, so another several hotel stays a year. Have never had anything taken, not even coins off the night stand. on the road, we stay at Marriotts, La Quinta, Drury, Doubletree, Embassy Suites