THe list could be exaustive. Read the boards and you will learn alot!
General
1.Make restaurant reservations nowat all parks if you will do a table service.
2. Be farmiliar with which days spectromagic parade is at MK and which day the fatasmic show is at hollywood studios. These are popular shows but they only do them on select days. If you do not have a hopper go to them on these days to see the shows.(Some people plan which parks they go to for various days before arrival this is once reason to do so if you choose.)
3. Look at maps before park arrival to refresh your memory.
4. Read up on what a fast pass is and utilize them on all rides that take them. They are free
5. Take your own snacks and water. Cups of Ice water is free there.
Magic Kingdom
1.I would suggest doing a character breakfast(winnie the pooh characters) at crystal palace on the day you go to MK so you can get early entrance (8:05 reservation). The dissers rave about this and you get to see main street almost empty which is amazing I hear. I have never done and will do this on my next trip.
2.I also know they have some sort of pirate experiece for boys at the Magic Kingdom. I cannot not thinik of the name but it seems they would enjoy this. They do pirate makeup etc. I have girls so I don't pay too much attention to this. Maybe another disser can enlighten you.
3. You will find character meet and greets at the town hall.
4. Don't miss Tom sawyer Island the boys will love it!
Hollywood
1. Go to toy story first or get a FP right away
In my opinion I would stay on property if only doing disney. I think it is easier. for many reasons, transportation being #1. Traffic is crazy and so are the exits in my opinion. Also, remember parking is 14.00 a day I think. The parking lots are also a long haul vs. bus pickup. Just my 2 cents though I know some will disagree with me. I have sayed at a awesome timeshare by downtown disney but I felt I was missing something. thought the rooms had advantages and it was like 2,000 square feet. I choose to stay on site. when on vacation I do not like to drive and I like my maid service and the resorts are amazing.