I'm usually fairly laid-back about germs (we rely on handwashing), but I'll admit I'm extra paranoid about stomach bugs. When DD was 20 months old, she spent the first two days of our Disney trip touching everything she could and even crawling on the floor at CRT, then the next three days throwing up. Our son will be 20 months old for our upcoming trip and I'll be traveling with plenty of wipes/sanitizer. I realize it doesn't kill all germs, but it's one brick in the wall. I recently found some wipes that claim they can kill germs on surfaces for up to 30 days (they deposit some kind of polymer on the surface wiped). I bought one to use on the doorknobs/remote at the hotel when we're in WDW. Can't hurt, could help.