You'll find a couple of Antonio's (Altamonte Springs, Dr. Phillips, Celebration) so that makes them a little chain, but they are locally owned. Good, basic Italian style food.
If you want loads of pub style food, Ale House is your place. Plentiful and cheap.
We like Ceviche in Downtown Orlando (on Church St.). It's a fabulous tapas place; makes Tu Tu Tango look like Mc Donald's!
We also like Bonefish, Melting Pot, Ruth's Chris, Charley's Steakhouse, Roy's and once in awhile, Season's 52. All are easily found in the vicinity of WDW.
If you want real local flavor head to Choctaw Willie's in beautiful downtown Winter Garden.
There are a couple of other nice locally owned small restaurants there too. :yes:
If you want a nice selection of to go food, try the new-ish Whole Foods at Sandlake and Turkey Lake. It has an extensive selection of prepared foods and you can eat in or take out.
There is also a Charley O's and Pei Wei in the same area. We like Pei Wei better than PF Changs.
If you want the ever popular Cheesecake Factory there is one at Millenia Mall. It's not a favorite of ours but many love it there. Also, there is a McCormick and Schmick's there too.
Joe's Crab Shack is nearer to DTD, and has some pretty good prices for crab pots and other seafood pots.
Avoid those all you can eat lobster places. The food is horribly overcooked and the sanitary aspects of the buffets are seriously wanting. They have quite a bit of trouble with the health department.
If you like Vietnamese food the area just east of I4 (exit at Amelia and take that to where it intersects 50/Colonial Dr. Take a RIGHT on Colonial) to Semoran is considered "Little Vietnam" and there are many restaurants there that serve Asian/Vietnamese/Thai food.
Bubbalou's Bodacious Barbecue is another local style chain that has some serious barbecue!
Don't go if you don't want messy food.
Hope that helps a bit!