Assuming you're there for the week - I wouldn't go to any of them! We usually hang out at our resort pool and then either go to DTD or to another resort for dinner in the evening. Sort of a "charge" to get ready for the rest of the trip! 3 years ago we went and ate at Palio's and then surprised DH with an Illuminations Cruise for his birthday on our first day there. That way we saw Illuminations without burning a day on the hoppers!
If you're just there for a few days and have to go somewhere it really depends on the people in your party! My suggestion is sort of the opposite of tcfdick! If you have small children I'd go to Epcot since that's usually not their "favorite" like MK is. Or if you've been before - go to whatever park has something new since your last visit.