We have stayed at all the WDW deluxe resorts except Wilderness Lodge and have stayed at the Portofino.
The rooms at Portofino are slightly bigger and the bathrooms are also bigger. Overall, PBH was a really nice resort. However, the one BIG difference is that PBH has NO balconies. Since we love balconies, I prefer the WDW resorts. There is nothing better than sitting out at night looking over the Boardwalk or MK while the kids go to sleep.