Having stayed at both resorts, I do have to say that my personal preference is AKL. However, that doesn't mean that I wouldn't go back to POFQ!! We had a very enjoyable stay there too.
I think it is pretty hard to compare a moderate to a deluxe since they are pretty different. The deciding factor to me has to come down to affordability for a family. The other thought is how much time do you plan on spending at the resort? When we have a shorter stay or plan to really spend time at the parks, I don't mind the moderate. When we are there for several days, and plan to spend more time at the resort I want the advantages of the deluxe.
We have had very good experiences with the CMs at both resorts - in fact, I think we ended up with a very creative Mousekeeper when we were at POFQ, the most creative we've had at any resort. We always were excited to get back to the room to see what she had come up with for my ds's "pets".
We also really liked the boat to DD at POFQ, the grounds were very relaxing (well, my dh and two ds's actually ended up using the large courtyard as a football field), the pool was a fun theme for the kids.
We love returning to AKL though. For AKL, the animals make it a whole different type of resort. For my animal-loving ds, it is tops! (He was happy at POFQ when he was able to see the squirrels, rabbits and lizards!) The benefit of the extra restaurants was nice too. We really like Boma for both breakfast and dinner. I love having CMs to tell us about the animals and also to answer questions about their homeland (if they are from Africa). The pool is great with the zero-entry depth and it is fun to get out of the pool, walk over to see the animals, walk back and have a drink from the pool bar. The shop at AKL is the best - great CMs every time we have visited.
I think the buses at AKL were better than the ones at POFQ - simply because you don't stop anywhere on your way to the park. It was great to get on and off at the first stop. The POFQ bus (only one bus stop) makes a few stops (usually) at POR bus stops on the way to the parks, but on the way "home" it does stop at the POFQ first.