Any interest in WDW? You may be able to rent DVC points in the current environment. Getting a 1BR would give you a kitchen, laundry, separate spaces. Your spouse would have the option to use Disney transportation to go somewhere like Disney Springs during the day or use the pool at the resort. Saratoga Springs is walkable to Disney Springs and Old Key West runs a boat, and these would be two of the easiest resorts to book this late. You could book as a cash reservation, but renting DVC points would be cheaper and seemingly not too difficult now like it would normally be. Just be mindful that there is no canceling a DVC rental if you're not able to go (you can cancel if you book a cash reservation through Disney).
Also, John and Kevin from the DIS Unplugged podcast (the owners of the Dis Boards) own vacation rentals called Dreams Villas of Orlando. Full townhouses, great prices, and the complex has a pool and fitness center. I quickly glanced through the photos and don't see a dedicated desk/workspace in the units, but they do have a dining room table or snack bar where I know I could set up shop to work from home. There's also a clubhouse with tables.
I'd also suggest checking out the townhouse style rentals at Margaritaville Orlando and Westgate.
IMO, I think finding a separate desk/workspace at a vacation rental in Orlando may be a difficult task. These properties are catering towards families and vacationing folks. Properties that are catering towards business travelers would be inclined to have an ideal workspace, but that would also likely be typical hotel rooms that don't have a kitchen.