The first time we used a Disney pack-n-play, I brought sheets from home and bought a can of Lysol on the way to the resort. I just sprayed everything, since dd was 6 months old. The next time, I didn't even do that. The pack-n-plays looked clean to me. I personally don't think it is worth taking the pack-n-play- you run the risk of damage on the plane. The bag it comes in is flimsy. We took ours on a different trip where we didn't have a crib or pack-n-play and put it in a LLBean duffle and it ended up ripping the duffle during the flight. The feet of the Pack-n-play went through the end of the bag.