So if it's just 4 nights then you might actually be able to make the Chase card work. Looking at those days of the week in the preceding weeks, the pattern is off peak on weekdays, standard on Fridays and standard or peak on Saturday. So 180-190k total. Using the 50k FNC for the standard night that leaves 130-140k in points. The base earn rate on the Boundless (as well as both AmEx cards) is 2x. So the 5k MSR gets you at least 10k Bonvoy points + the 125k bonus so you'll have 135k to start. This strategy does rely on some nights being off peak.
If you don't want to chance it then the AmEx Business card would cover your bases better. Since you get 2 50k certs you'd need less points available for the remaining nights. The Business card also has additional bonus categories to earn more points - 4x for Restaurants, Gas stations, Shipping Providers, Wireless phone services purchased directly from service providers in addition to the 2x on everything.
Good luck choosing! We're here if you have any questions.