The Hyatt Hotel is nice! Right on Newport's Back Bay, and close to Fashion Island (but not on the ocean).
Also, up in Huntington Beach, there are a couple of nice hotels, (The Hilton Waterfront is one), and in Laguna Beach, the three biggies are the Montage, the Ritz Carlton, and the St. Regis. The last three are quite expensive, just depends on what your budget is.
I would suggest you look at Expedia.com, and see what they offer. They have rates, pictures and reviews on most properties!
Happy Honeymooning!