The Five Guys closest to WDW is on Sand Lake, in the backside of the shopping plaza that has the Homegoods and Toojays Deli, across the street from Barnes & Noble. Take Apopka-Vineland north and turn right at Sand Lake, and the plaza is over the hill on the left, or take I-4 east and take a left (I assume) on Sand Lake, and the plaza is on the right after the fancy-schmancy strip mall.
I got violently ill from my one and only Five Guys experience, so I'll stick with Ale House, thank you very much. Or Hops, if I'm in Ocala. Anyone know what happened to the Hops in Orlando? It was a microbrewery type restaurant with great burgers.