We live in Princeton, NJ and we leave around 3:30 AM to avoid all traffic around DC and Baltimore. That also gets us barely around DC by rush hour, but I wouldn't leave any earlier, I need some sleep before that long drive. We drove all the way to Brunswick last time, arriving around 5:30 PM. We also stop for a full breakfast, lunch break (usually a McDonalds with a playland for the kids to run off some steam) and then when we arrive at our destination for the night. At all stops, we fill up the tank, so we can just keep going until the next one, it works for us. This year, we've leaving on a Saturday, so that helps with rush hour in DC and we're leaving around 4:30 AM. We're also stopping in Savannah (about 1 hour north of Brunswick) since last year we were basically spent by Savannah, but pushed to Brunswick since we were driving to South Florida first and wanted to get that extra hour in. I see you have a child and I can't express enough how our DVD player saved our lives!!!! Our kids (2 and 5 at the time) just sat there and watched movies the entire time!! They were great during the ride and never complained about the drive at all!!!