I believe Myrtle Beach is about an hor and a half off of route 95. Not sure if this is a definite part of your plan?
We are from MA and drive to Hilton Head frequently. We stop in Lumberton, NC. We live near Sturbridge and it is 13 hours. We leave at 6am which avoids all the rush hour traffic for Hartford, NY, Baltimore and Dc. We usually hit Lumberton aroun 7pm. (Just got back last Friday)
Two hotels I would recommend....basic but clean are the Best Western and Comfort Inn. There are two Comfort Inns....one is good and one is pretty bad. Check tripadvisor for the reviews. Sorry but I forget the address for the good one.
Hope this helps!
PS. Savannah is also a nice stop over. That is about four hours south of Lumberton but close to Route 95.
Have a great trip!!