Daytona Beach is only about 1 1/2 hours from WDW. Are you going to spend some time at the beach or to get a night's sleep before going to the parks?
I would drive the rest of the way and just extend your stay where ever you are staying at WDW.
And for the drive home I would do a non-stop.
I live in CT and make the drive to WDW at least once a year. I drive straight through between 17 and 20 hours depending on the traffic. The thought of driving from SC to WDW sounds like a drive around the block to me.