No. If I wake up at 2:00 am with a craving for Taco Bell, I can just jump in the car and swing through the drive thru in my PJs. I'm free to come and go at any time in a regular hotel room or in my house.
That being said we'd probably have to turn down the Castle room if we were ever offered the opportunity. We both smoke and there's no smoking in any hotel room on WDW property.