Comes down to what you value more, convenience to 2 parks, or a better hotel experience.
CBR obviously wins for the transportation to those two parks.
I think I have the tower winning in almost everything else, but it's subjective. CSR has a better selection of lounges, bars and restaurants, but Banana Cabana and Sebastians at CBR are no slouches. I think I preferred the main pool at CSR more, but we are more quiet pool people anyway. Transportation to the other two parks can really depend on your location at CBR, for the tower its short covered walk to the bus stop. It is the last stop on the way to and from the parks (it is first stop for springs though), we never had a seat when rope dropping a park because it was the last stop. We appreciated the walkway being covered and that the stop was by the old main lobby that had a bottle filler.
I honestly don't think you can go wrong at any Disney moderate. I can give pros/cons for everyone.