For my autograph book, I copied the 4x6 designs into word and used regular sized paper.
On another DISer's recommendation, I did this:
Here's what I did with them:
I printed out half of the pages, then I turned the paper around and printed the other half - they were both on the same side of the paper, but one was upside down, if that makes sense. That way I could save paper.
Also, I made a page that has no character on it, just a design on the page. I printed a couple of those out for any characters we encountered that I did not make a page for.
I used cardstock, not regular paper, so it was more sturdy.
One person also recommended to save $$ you could Then, I cut the paper in half, punched holes in each page and put 2 large book rings in each hole (like what is in a binder, but these are loose).
There were so many pages, that it was thick enough to make it easy to write on, but you could flip the pages all the way around so it was flat.
I am also taking my book to Staples for them to do the binding and have the front cover laminated.
Currently several people here are doing some super cute autograph disigns....check out these pages
Chaoscent (Penny)
http://s226.photobucket.com/albums/dd181/Chaos1Cent/?start=0
Are We There Yet
http://s345.photobucket.com/albums/p379/ljcollins_2008/Character%20Autograph%20Pages/
Not sure she is actively DISigning, but here is kimfaver
http://s296.photobucket.com/albums/mm191/kimfawver/blank%20autograph%20pages/