This is much too general a question to answer. It would depend on what the disability was and how severely it affected the person.
I am disabled, in that I needed a wheelchair most of the time. But the only attraction I can't do is the treehouse, because of the stairs. Others who can't transfer from a chair unassisted have a longer list of rides they can't do.
Autism is a spectrum. Some can ride everything, some can only do some of them.