Once I took the 111 from the airport, with a medium sized checked luggage. It's a city bus, so you will need to keep the path clear by keeping the luggage out of the center aisle. I found a spot as far back as I could, out of the way of the doors. Like someone else said, the airport busses that don't have luggage racks are more so for people to get to and from work or other business at the airport.