DH and I have done Disney without DD twice, and both were a blast.
The 1st time, we stayed at PO-R (then DXL) in Alligator Bayou. We were only there for 5 days, but we made the most of them. We took advantage of the early entry mornings, took our time shopping at DTD, and ate at Fulton's (yum), had strawberry margaritas at Capt Jacks while watching the sunset. Spent an evening designing and riding Virtual Space Mountain at DQ, rented paddle boats and paddled down the Sassagoula River, discovered Narcoosee's and their yummy Margaritas, and yards of beer (only DH did that). And of course, had to do a character meal, and eat at Cape May Cafe for the Clam Bake (yum!)
Our second trip was last January, and we stayed in the Contemporary. LOVE that resort! Huge rooms, and can't beat the convenience. It was cold and somewhat rainy while we were there, but that didn't stop us (although I couldn't bring myself to use the hot tubs). We did e ticket night at MK, slowly and thoroughly enjoyed AK. Rode ToT and RnR over and over, drank our way around the World Showcase, ate at Narcoosees for the 1st time (I highly recommend doing this right as the sun is setting! The view of the MK is breathtaking), stopped at the coffee bar every morning on the way to the parks, rode the monorail, just for the heck of it. Drove over to Celebration to see what was there. Of course, we ate at Cape May again... can't go to WDW and not eat there! Discovered other restaurants that DD wouldn't be interested in, such as Tempura Kiku, and Le Cellier.
We played, ate, and drank, and had a wonderful time. We look forward to doing it again soon!