Cranbiz, anyone wishing to use the I-4 routing does not need to stay on Lake Mary Blvd for 8 miles to get to I-4. While that routing does avoid ALL tolls, drivers can hop onto TOLL 417 northbound from Lake Mary Blvd. just outside the airport and pay one $.50 toll and that will take them to I-4 in a quarter of the time it would take if they stayed on Lake Mary Blvd.
LisaNJ25, from Orange City your best bet is I-4 all the way to Disney since Orange City is right along I-4. But as with everyone else, if you're journey is going to send you across Orlando between 7am and 9am you'd best use the TOLL 417 beltway and go around Orlando. Likewise absolutely don't try to drive back to Orange City between 3pm and 7pm otherwise you'll face gridlock!
nkjzmom, at 5pm on a Thursday you'd be far better off to take TOLL 417 southbound direct to Disney and completely bypass downtown Orlando. But if you're flight is running late and by the time you get your car you'd cross Orlando around 7pm, the I-4 option is viable.
Everyone, be forewarned that between Sanford and Disney there are 5-6 separate toll plazas when using TOLL 417. The tolls range between $.50 to $1.75 each and there can be backups at the manual lanes. Bring a roll of quarters and you can use the exact change coin lanes and save time. BTW, TOLL 417 is also signed as the "Seminole Expressway" in Seminole County and as the "Central Florida GreeneWay" in Orange County.
BobK/Orlando