TSA at MCO does seem to really vary. In August I asked about the families and medical needs line since I didn't see any signs (I like to use it because I figure we've got plenty of medications and I never know if I'll need extra time for DD14 to talk with the TSA agent (she's autistic) and I don't want to hold up busier travellers). The agent I asked laughed and said we're near Disney World and half the people are families so all lines are family lines. In the past there was always one on either side. The trip where we used a wheelchair we just walked over to the family and medical needs line as the sign clearly showed an image of somebody with mobility needs. There was no special shorter line or access. My experience definitely mirrored WheeledTraveler's. There was one time where the crowd was huge and we hung back a bit because DD14 was getting nervous about the mob looking area and we got talking with a TSA agent asking if there was any particular agent who would be more patient wiht DD14. She asked us to hold on a minute and went to talk to somebody and then came back and escorted us to the employee line. We never expected that (I honestly just wanted her opinion about which agent would be more likely to be patient with her because she was getting aggitated by just looking at the mob). This sort of thing can happen but I NEVER expect it or count on it. For our upcoming trip we're flying Jet Blue for the first time and paid for those bigger seats that also come with access to some kind of expidited line through security. I don't know how exactly that works but that alone is worth the upgrade fee to me. The extra leg room and early boarding is bonus. I can't wait to see how it works.