Just want to chime in on the Comfort Suites Maingate East. We stayed there over Labor Day Weekend and will stay there again in November. The breakfast is good...lots of choices....scrambled or hard boiled eggs, sausage or bacon, biscuits and gravy, fresh fruit, mickey waffles, coffee, hot chocolate. There was a lot to choose from. Also, their pool is open 24 hours a day. The room is a good size...2 queen beds (very comfortable), pull out sofabed, refrigerator, microwave and some cupboards and a sink in the kitchen area. Flat screen TV and a small table with 2 chairs. The pics on their website are very accurate.
The only complaints I have are that the elevators are really slow. We were on the 7th floor with a great view of Old Town and took the stairs most of the time as the elevators were so very slow. The other issue was with parking on Saturday night. People going to Old Town parked in the hotel parking and with the hotel being filled to capacity that night, by 10pm there were only a few spots left in the parking lot.
That being said, DH said we'd stay there every trip. The hotel was clean, the room was very clean and for the 5 of us, we had enough space.
If you book through the hotel website and not the main comfort suites website, the rates are better....more discounted rates for specific groups (AAA, Fla. residents, etc.)
If you are looking for more space, then I would agree with other posters and rent a condo/house. We did that over the summer for a week with the extended family (12 of us). It was nice to have all that space and a pool right out the back door, but for me, it didn't feel like vacation since I was cooking and cleaning. I like eating out on vacation (pretty much the only time we do) and having daily maid service on vacation...I'm one of "those" type of people